Department of Biotechnology
Institute for Biochemistry, Biotechnology and Bioinformatics



Phone: +49.531.391.5744
Fax: +49.531.391.5763

Research interests

Clostridium difficile, Antibody Engineering, tick vaccines (BMBF GO-Bio8 project)

Curriculum vitae
Studies of Biotechnology (B. Sc.) at Technische Universität Braunschweig
Studies of Biotechnology (M. Sc.) at Technische Universität Braunschweig
Masters Thesis: "Selektion neutralisierender Antikörperfragmente gegen Hepatitis C Hüllproteine aus einer humanen Antikörper-Gen-Biobliothek" at Institut für Biochemie, Biotechnologie und Bioinformatik / Abteilung Biotechnologie
Research internship at Novartis Pharma in Basel
PhD student at Institut für Biochemie, Biotechnologie und Bioinformatik / Abteilung Biotechnologie
since 2018
Postdoc tick vaccine project



  • Russo, G., Fühner, V., Frenzel, A., Hust, M. and Dübel, S. (2019) Parallelized Microscale Expression of Soluble scFv. Metheds Molecular Biology 2025: 203-211
  • Fühner, V., Heine, P.A., Zilkens, K., Meier, D., Roth, K.D.R., Moreira, G.M.S.G., Hust, M. and Russo, G. (2019). Epitope Mapping via Phage Display from single gene libraries. Methods Molecular Biology 1904: 353-375
  • Fühner, V., Heine, P.A., Helmsing, S., Goy, S., Heidepriem, J., Loeffler, F.F., Dübel, S., Gerhard, R. and Hust, M. (2018). Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile. Frontiers in Microbiology 9: 2908
  • Chung, S.Y., Schöttelndreier, D., Tatge, H., Fühner, V., Hust, M., Beer, L.A. and Gerhard, R. (2018). The conserved Cys-2232 in Clostridioides difficile toxin B modulates oligomerization and receptor binding. Frontiers in Microbiology 9: 2314
  • Beer, L.A., Tatge, H., Schneider, C., Ruschig, M., Hust, M., Barton, J., Thiemann, S., Fühner, V., Russo, G. and Gerhard, R. (2018). The binary toxin CDT of Clostridium difficile as tool for intracellular delivery of bacterial glucosyltransferase domains. Toxins 10: 225
  • Moreira, G.M.S.G., Fühner, V. and Hust, M. (2018). Epitope Mapping by Phage Display. Phage display, Ed: Lim, T.S. and Hust, M., Methods Molecular Biology 1701: 497-518
  • Kuhn, P., Fühner, V., Moreira, G.M.S.G., Frenzel, A., Miethe, S. and Hust, M. (2016). Recombinant Antibodies for Diagnostics and Therapy against Pathogens and Toxins generated by Phage Display.  Proteomics - Clinical Applications 10: 922-948
  • Rohrbeck, A., Fühner, V., Schröder, A., Hagemann, S., Vu, X.-H., Berndt, S., Hust, M., Pich, A. and Just, I. (2016). Detection and Quantification of ADP-Ribosylated RhoA/B by Monoclonal Antibody. Toxins 8:100
  • Unkauf, T., Miethe, S. Fühner, V., Schirrmann, T., Frenzel, A. and Hust, M. (2016). Generation of recombinant antibodies against toxins and viruses by phage display for Diagnostics and Therapy.  Advances in Experimental Medicine and Biology 917: 55-76
  • Hofmann, I., Wen, Y., Ciferri, C., Schulze, A., Fühner, V., Leong, M., Gerber, A., Gerrein, R., Nandi, A., Lilja, A.E., Carfi, A., Laux, H. (2015). Expression of the Human Cytomegalovirus Pentamer Complex for vaccine use in a CHO system. Biotechnol. Bioeng. 112: 2505-2515