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 Dr. VIOLA FÜHNER
 Postdoc
Room:108
Phone: +49.531.391.5744
Fax: +49.531.391.5763
e-mail: v.fuehner@tu-bs.de
Research interests
Clostridium difficile, Antibody Engineering, tick
vaccines (BMBF GO-Bio8 project)
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Curriculum vitae
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2008-2011
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Studies of
Biotechnology (B. Sc.) at Technische
Universität
Braunschweig |
2011-2013
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Studies of
Biotechnology (M. Sc.) at Technische
Universität
Braunschweig
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2012/2013
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Masters Thesis:
"Selektion neutralisierender
Antikörperfragmente gegen Hepatitis C
Hüllproteine aus einer humanen
Antikörper-Gen-Biobliothek" at Institut für
Biochemie, Biotechnologie und Bioinformatik
/ Abteilung
Biotechnologie |
2013
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Research
internship at Novartis Pharma in Basel
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2014-2019
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PhD student at
Institut für Biochemie, Biotechnologie und
Bioinformatik / Abteilung
Biotechnologie |
since 2018
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Postdoc tick
vaccine project
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Publications
- Russo, G., Fühner, V., Frenzel, A., Hust, M.
and Dübel, S. (2019) Parallelized Microscale
Expression of Soluble scFv. Metheds
Molecular Biology 2025: 203-211
- Fühner, V., Heine, P.A., Zilkens, K., Meier,
D., Roth, K.D.R., Moreira, G.M.S.G., Hust, M.
and Russo, G. (2019). Epitope Mapping via
Phage Display from single gene libraries. Methods Molecular Biology 1904:
353-375
- Fühner, V., Heine, P.A., Helmsing, S., Goy,
S., Heidepriem, J., Loeffler, F.F., Dübel, S.,
Gerhard, R. and Hust, M. (2018). Development
of Neutralizing and Non-neutralizing
Antibodies Targeting Known and Novel Epitopes
of TcdB of Clostridioides difficile.
Frontiers in Microbiology 9:
2908
- Chung, S.Y., Schöttelndreier, D., Tatge, H.,
Fühner, V., Hust, M., Beer, L.A. and Gerhard,
R. (2018). The conserved Cys-2232 in
Clostridioides difficile toxin B modulates
oligomerization and receptor binding. Frontiers
in Microbiology 9: 2314
- Beer, L.A., Tatge, H., Schneider, C.,
Ruschig, M., Hust, M., Barton, J., Thiemann,
S., Fühner, V., Russo, G. and Gerhard, R.
(2018). The binary toxin CDT of Clostridium
difficile as tool for intracellular delivery
of bacterial glucosyltransferase domains. Toxins 10: 225
- Moreira, G.M.S.G., Fühner, V. and Hust, M.
(2018). Epitope Mapping by Phage Display.
Phage display, Ed: Lim, T.S. and Hust, M., Methods Molecular Biology
1701: 497-518
- Kuhn, P., Fühner, V., Moreira, G.M.S.G.,
Frenzel, A., Miethe, S. and Hust, M. (2016).
Recombinant Antibodies for Diagnostics and
Therapy against Pathogens and Toxins generated
by Phage Display. Proteomics - Clinical
Applications
10: 922-948
- Rohrbeck, A., Fühner, V., Schröder, A.,
Hagemann, S., Vu, X.-H., Berndt, S., Hust, M.,
Pich, A. and Just, I. (2016). Detection and
Quantification of ADP-Ribosylated RhoA/B by
Monoclonal Antibody. Toxins
8:100
- Unkauf, T., Miethe, S. Fühner, V.,
Schirrmann, T., Frenzel, A. and Hust, M.
(2016). Generation of recombinant antibodies
against toxins and viruses by phage display
for Diagnostics and Therapy.
Advances in Experimental
Medicine and Biology 917: 55-76
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Hofmann, I., Wen, Y., Ciferri, C., Schulze,
A., Fühner, V., Leong, M., Gerber, A.,
Gerrein, R., Nandi, A., Lilja, A.E., Carfi,
A., Laux, H. (2015). Expression of the Human
Cytomegalovirus Pentamer Complex for vaccine
use in a CHO system. Biotechnol.
Bioeng. 112: 2505-2515
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